This article is an overview of trace mineral nutrition, disease association with dietary inadequacy of trace minerals, and the associated diseases in goats. The trace minerals most commonly associated with deficiency-related diseases encountered in clinical veterinary medicine, Copper, Zinc, and Selenium, are discussed in greater detail than those less commonly associated with diseases. However, Cobalt, Iron, and Iodine are also discussed. The signs of deficiency-associated diseases, along with diagnostic evaluation to confirm such diseases, are also discussed.