This article introduced a systematic approach to matching composite and tooth shades to create esthetic restorations that visually integrate seamlessly with the patient's tooth and surrounding dentition. A basic explanation of color science was presented to aid the clinician in adopting this systematic approach to color matching. To demonstrate the need for custom shade guides, an objective analysis of composites from different companies was performed by recording the color coordinate values of multiple composites and then calculating CIEDE2000 color differences. Different locations on the tooth were analyzed using the same identified shade from different companies, as well as using the same composite shade applied in different thicknesses. A case report documented the clinical application of these shade matching techniques. Shade matching, particularly in the anterior esthetic region, can be challenging, which can result in patient dissatisfaction with the esthetic result. Stock shade tabs are not a reliable indicator of actual composite shades. The most predictable esthetic results were achieved by using custom shade guides as an entry point, followed by a direct composite color mockup intraorally. To consistently meet the esthetic demands of today's patients, dentists need reliable tools when selecting a composite shade for restorations. Composites with the same shade designation vary in color and shade designation cannot be relied upon for accurate shade selection. The use of custom shade guides and an intra-oral mockup can enhance the esthetic outcome.