-transparent.png){kind=logo}
Of 41 children, aged 5-15 years, referred consecutively because of recurrent urinary tract infections (UTIs) and/or enuresis, 18 (44%) showed detrusor instability (DI) in at least 2 of 6 CO2 cystometries. One child was excluded from the study because of lack of follow-up. Four children with less pronounced DI (instability during less than or equal to 50% of the cystometries performed) and frequent UTIs were given antibiotics prophylactically for 3 months. In the remaining 13 children, DI was found during more than half the cystometries performed, and 11 of these children, who also had urge incontinence, were treated with emepronium bromide, 400-600 mg daily (10-12 mg/kg) for 3 months. In 7 of the patients this treatment was supplemented by antibiotics prophylactically because of frequent UTIs. Two children with special problems received other types of treatment. All children were free from symptoms at a clinical check-up 6 months later, 95% confidence limits 0-20%.
N Qvist, and
K K Nielsen, and
E S Kristensen, and
D Ehlers, and
K M Jensen, and
T Krarup, and
J Christoffersen
September 1987,
Archives of disease in childhood,
N Qvist, and
K K Nielsen, and
E S Kristensen, and
D Ehlers, and
K M Jensen, and
T Krarup, and
J Christoffersen
August 1993,
Urology,
N Qvist, and
K K Nielsen, and
E S Kristensen, and
D Ehlers, and
K M Jensen, and
T Krarup, and
J Christoffersen
January 1989,
Revista chilena de pediatria,
N Qvist, and
K K Nielsen, and
E S Kristensen, and
D Ehlers, and
K M Jensen, and
T Krarup, and
J Christoffersen
January 2009,
JNMA; journal of the Nepal Medical Association,
N Qvist, and
K K Nielsen, and
E S Kristensen, and
D Ehlers, and
K M Jensen, and
T Krarup, and
J Christoffersen
September 2013,
Iranian journal of kidney diseases,
N Qvist, and
K K Nielsen, and
E S Kristensen, and
D Ehlers, and
K M Jensen, and
T Krarup, and
J Christoffersen
May 1967,
The Practitioner,
N Qvist, and
K K Nielsen, and
E S Kristensen, and
D Ehlers, and
K M Jensen, and
T Krarup, and
J Christoffersen
February 2000,
BJU international,
N Qvist, and
K K Nielsen, and
E S Kristensen, and
D Ehlers, and
K M Jensen, and
T Krarup, and
J Christoffersen
January 1975,
Acta paediatrica Scandinavica,
N Qvist, and
K K Nielsen, and
E S Kristensen, and
D Ehlers, and
K M Jensen, and
T Krarup, and
J Christoffersen
January 2002,
Medical science monitor : international medical journal of experimental and clinical research,
N Qvist, and
K K Nielsen, and
E S Kristensen, and
D Ehlers, and
K M Jensen, and
T Krarup, and
J Christoffersen
June 2015,
BMJ clinical evidence,
