Biomaterial Database

Correlative studies of cochlear neuronal loss with speech discrimination and pure-tone thresholds. 1986

M Pauler, and H F Schuknecht, and A R Thornton

Correlations were made between speech discrimination scores, pure-tone thresholds, and neuronal populations in 28 cochleae which were removed postmortem from elderly patients who had known premortem audiometric records. The predominant pathology present was loss of cochlear neurons. The capability for speech discrimination correlated directly with the innervation density of the 15- to 22-mm region (segment III) of the cochlea. Speech discrimination scores showed an inverse relationship to pure-tone thresholds in the middle frequency range of 1 kHz to 2 kHz.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D009474	Neurons	The basic cellular units of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the NERVOUS SYSTEM.	Nerve Cells,Cell, Nerve,Cells, Nerve,Nerve Cell,Neuron
D003051	Cochlea	The part of the inner ear (LABYRINTH) that is concerned with hearing. It forms the anterior part of the labyrinth, as a snail-like structure that is situated almost horizontally anterior to the VESTIBULAR LABYRINTH.	Cochleas
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000368	Aged	A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available.	Elderly
D001299	Audiometry	The testing of the acuity of the sense of hearing to determine the thresholds of the lowest intensity levels at which an individual can hear a set of tones. The frequencies between 125 and 8000 Hz are used to test air conduction thresholds and the frequencies between 250 and 4000 Hz are used to test bone conduction thresholds.	Audiometries
D001301	Audiometry, Pure-Tone	Measurement of hearing based on the use of pure tones of various frequencies and intensities as auditory stimuli.	Audiometry, Bekesy,Audiometry, Pure Tone,Bekesy Audiometry,Pure-Tone Audiometry
D013067	Speech Perception	The process whereby an utterance is decoded into a representation in terms of linguistic units (sequences of phonetic segments which combine to form lexical and grammatical morphemes).	Speech Discrimination,Discrimination, Speech,Perception, Speech