Biomaterial Database

Potential halogenated industrial carcinogenic and mutagenic chemicals. IV. Halogenated aryl derivatives. 1979

L Fishbein

A variety of halogenated aryl derivatives possess significant activity as solvents for pesticides, heat transfer agents, pesticide intermediates, additives for rubber products, intermediates in organic synthesis and as insect repellants and deodorants. Ortho- and para-dichlorobenzenes; 1,2,4-trichloro- and hexachlorobenzene, as well as bromobenzenes and benzylchloride were reviewed principally in terms of their synthesis, areas of utility, stability, distribution, reactivity, levels of exposure, populations at risk, metabolism, carcinogenicity and mutagenicity.

UI	MeSH Term	Description	Entries
D009153	Mutagens	Chemical agents that increase the rate of genetic mutation by interfering with the function of nucleic acids. A clastogen is a specific mutagen that causes breaks in chromosomes.	Clastogen,Clastogens,Genotoxin,Genotoxins,Mutagen
D001969	Bromobenzenes	Derivatives of benzene in which one or more hydrogen atoms on the benzene ring are replaced by bromine atoms.
D002274	Carcinogens, Environmental	Carcinogenic substances that are found in the environment.	Environmental Carcinogens
D002722	Chlorobenzenes	Aromatic organic compounds with the chemical formula C6H5Cln.
D004781	Environmental Exposure	The exposure to potentially harmful chemical, physical, or biological agents in the environment or to environmental factors that may include ionizing radiation, pathogenic organisms, or toxic chemicals.	Exposure, Environmental,Environmental Exposures,Exposures, Environmental
D006581	Hexachlorobenzene	An agricultural fungicide and seed treatment agent.	HCB
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D006846	Hydrocarbons, Halogenated	Hydrocarbon compounds with one or more HYDROGEN atoms substituted with HALOGENS.	Halogenated Hydrocarbons
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D001593	Benzyl Compounds	Benzene derivatives that contain a benzyl group with the general formula Phenyl-CH2-R.	Compounds, Benzyl