Biomaterial Database

Central amygdala CRF1 cells control nociception and anxiety-like behavior. 2024

Marcus M Weera, and Nicholas W Gilpin

Department of Physiology, School of Medicine, Louisiana State University Health Sciences Center, New Orleans, LA, 70112, USA. mweera@lsuhsc.edu.

UI	MeSH Term	Description	Entries
D003346	Corticotropin-Releasing Hormone	A peptide of about 41 amino acids that stimulates the release of ADRENOCORTICOTROPIC HORMONE. CRH is synthesized by neurons in the PARAVENTRICULAR NUCLEUS of the HYPOTHALAMUS. After being released into the pituitary portal circulation, CRH stimulates the release of ACTH from the PITUITARY GLAND. CRH can also be synthesized in other tissues, such as PLACENTA; ADRENAL MEDULLA; and TESTIS.	ACTH-Releasing Hormone,CRF-41,Corticotropin-Releasing Factor,Corticotropin-Releasing Hormone-41,ACTH-Releasing Factor,CRF (ACTH),Corticoliberin,Corticotropin-Releasing Factor-41,ACTH Releasing Factor,ACTH Releasing Hormone,Corticotropin Releasing Factor,Corticotropin Releasing Factor 41,Corticotropin Releasing Hormone,Corticotropin Releasing Hormone 41
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D001007	Anxiety	Feelings or emotions of dread, apprehension, and impending disaster but not disabling as with ANXIETY DISORDERS.	Angst,Anxiousness,Hypervigilance,Nervousness,Social Anxiety,Anxieties, Social,Anxiety, Social,Social Anxieties
D001522	Behavior, Animal	The observable response an animal makes to any situation.	Autotomy Animal,Animal Behavior,Animal Behaviors
D059225	Nociception	Sensing of noxious mechanical, thermal or chemical stimuli by NOCICEPTORS. It is the sensory component of visceral and tissue pain (NOCICEPTIVE PAIN).	Nociperception,Nociceptions,Nociperceptions
D018019	Receptors, Corticotropin-Releasing Hormone	Cell surface proteins that bind corticotropin-releasing hormone with high affinity and trigger intracellular changes which influence the behavior of cells. The corticotropin releasing-hormone receptors on anterior pituitary cells mediate the stimulation of corticotropin release by hypothalamic corticotropin releasing factor. The physiological consequence of activating corticotropin-releasing hormone receptors on central neurons is not well understood.	CRH Receptors,Corticotropin Releasing-Factor Receptor,Corticotropin Releasing-Hormone Receptors,Receptors, CRH,CRF Receptor,CRF Receptors,CRH Receptor,Corticotropin Releasing-Factor Receptors,Corticotropin Releasing-Hormone Receptor,Receptors, CRF,Corticotropin Releasing Factor Receptor,Corticotropin Releasing Factor Receptors,Corticotropin Releasing Hormone Receptor,Corticotropin Releasing Hormone Receptors,Corticotropin-Releasing Hormone Receptors,Hormone Receptors, Corticotropin-Releasing,Receptor, CRF,Receptor, CRH,Receptor, Corticotropin Releasing-Factor,Receptor, Corticotropin Releasing-Hormone,Receptors, Corticotropin Releasing Hormone,Receptors, Corticotropin Releasing-Factor,Receptors, Corticotropin Releasing-Hormone,Releasing-Factor Receptor, Corticotropin,Releasing-Factor Receptors, Corticotropin,Releasing-Hormone Receptor, Corticotropin,Releasing-Hormone Receptors, Corticotropin
D066274	Central Amygdaloid Nucleus	A nucleus located in the caudal half of the amygdala. It is a primary region involved in controlling responses and receives many intrinsic GABAergic amygdaloid connections.	Central Amygdala Nucleus,Central Amygdala,Central Nucleus of Amygdala,Central Nucleus of the Amygdala,Amygdala Central Nucleus,Amygdala Nucleus, Central,Amygdala, Central,Amygdalas, Central,Amygdaloid Nucleus, Central,Central Amygdalas,Nucleus, Central Amygdala,Nucleus, Central Amygdaloid