Recent Study Showing Rapidly Decreasing Levels of LPS Using the Efferon LPS Using LAL Assay But Is LAL Assay Reliable to Detect Endotoxin?
2023
Patrick M Honore, and
Emily Perriens, and
Wissal El Ouahidi, and
Amina El Bachti, and
Aliyah Tondeur, and
Sydney Blackman
UI
MeSH Term
Description
Entries
D008033
Limulus Test
Sensitive method for detection of bacterial endotoxins and endotoxin-like substances that depends on the in vitro gelation of Limulus amebocyte lysate (LAL), prepared from the circulating blood (amebocytes) of the horseshoe crab, by the endotoxin or related compound. Used for detection of endotoxin in body fluids and parenteral pharmaceuticals.
Limulus Tests,Test, Limulus,Tests, Limulus
D008070
Lipopolysaccharides
Lipid-containing polysaccharides which are endotoxins and important group-specific antigens. They are often derived from the cell wall of gram-negative bacteria and induce immunoglobulin secretion. The lipopolysaccharide molecule consists of three parts: LIPID A, core polysaccharide, and O-specific chains (O ANTIGENS). When derived from Escherichia coli, lipopolysaccharides serve as polyclonal B-cell mitogens commonly used in laboratory immunology. (From Dorland, 28th ed)
Lipopolysaccharide,Lipoglycans
D004731
Endotoxins
Toxins closely associated with the living cytoplasm or cell wall of certain microorganisms, which do not readily diffuse into the culture medium, but are released upon lysis of the cells.
Endotoxin
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Patrick M Honore, and
Emily Perriens, and
Wissal El Ouahidi, and
Amina El Bachti, and
Aliyah Tondeur, and
Sydney Blackman