-transparent.png){kind=logo}
In order to evaluate further the possibility that transient hypothyroidism and hyperthyrotropinemia in newborn infants could result from a state of relative iodine deficiency, the urinary concentration of iodine, used as an index of the dietary intake of iodine was determined in casual urine samples collected in 1,076 full-term infants aged 3-6 days in 16 cities in 10 different European countries and in Toronto, Canada. In addition, the results obtained by programs of systematic neonatal screening for congenital hypothyroidism in the same areas were compared. There were marked regional differences in iodine nutrition during the neonatal period in Europe (median urinary iodine: 16.2 micrograms/dl in Rotterdam, the Netherlands, and 1.1 micrograms/dl in Freiburg, FRG. A low iodine supply in newborn populations was accompanied by, and probably explained, an elevated frequency of transient disorders of thyroid function in young infants. Iodine prophylaxis is urgently needed in some European countries not only for the prevention of goiter, but mostly for the prevention of impairment of thyroid function during the critical period of brain development.
F Delange, and
P Heidemann, and
P Bourdoux, and
A Larsson, and
R Vigneri, and
M Klett, and
C Beckers, and
P Stubbe
February 2000,
The Journal of clinical endocrinology and metabolism,
F Delange, and
P Heidemann, and
P Bourdoux, and
A Larsson, and
R Vigneri, and
M Klett, and
C Beckers, and
P Stubbe
December 2007,
Public health nutrition,
F Delange, and
P Heidemann, and
P Bourdoux, and
A Larsson, and
R Vigneri, and
M Klett, and
C Beckers, and
P Stubbe
December 1995,
Journal of obstetrics and gynaecology (Tokyo, Japan),
F Delange, and
P Heidemann, and
P Bourdoux, and
A Larsson, and
R Vigneri, and
M Klett, and
C Beckers, and
P Stubbe
June 2023,
Biological trace element research,
F Delange, and
P Heidemann, and
P Bourdoux, and
A Larsson, and
R Vigneri, and
M Klett, and
C Beckers, and
P Stubbe
January 1998,
Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists,
F Delange, and
P Heidemann, and
P Bourdoux, and
A Larsson, and
R Vigneri, and
M Klett, and
C Beckers, and
P Stubbe
November 1999,
The American journal of clinical nutrition,
F Delange, and
P Heidemann, and
P Bourdoux, and
A Larsson, and
R Vigneri, and
M Klett, and
C Beckers, and
P Stubbe
January 1978,
Minerva pediatrica,
F Delange, and
P Heidemann, and
P Bourdoux, and
A Larsson, and
R Vigneri, and
M Klett, and
C Beckers, and
P Stubbe
October 1979,
Clinical endocrinology,
F Delange, and
P Heidemann, and
P Bourdoux, and
A Larsson, and
R Vigneri, and
M Klett, and
C Beckers, and
P Stubbe
March 2014,
European journal of clinical nutrition,
F Delange, and
P Heidemann, and
P Bourdoux, and
A Larsson, and
R Vigneri, and
M Klett, and
C Beckers, and
P Stubbe
March 1967,
Acta paediatrica Scandinavica,
