-transparent.png){kind=logo}
Cholinergic receptors present in three medullary nuclei namely, the nucleus tractus solitarii (NTS), nucleus ambiguous (AMB) and the dorsal motor nucleus of the vagus nerve (DMV) have been studied with regard to their role in regulation of heart rate (HR), blood pressure (BP) and baroreceptor reflex activation induced bradycardia in cats. Microinjection of carbachol into NTS was without effect while administration of carbachol or pilocarpine into AMB and DMV elicited dose related decrease in HR without affecting BP. These effects were completely antagonized by ethylbenztropine. Bilateral muscarinic cholinoceptor blockade of either AMB or DMV, with ethylbenztropine, produced a partial inhibition of the baroreflex bradycardia while intracisternal ethylbenztropine completely abolished this reflex response. Involvement of muscarinic cholinoceptors of AMB or DMV in baroreflex mediated adjustments of HR is therefore suggested.
S Gurtu, and
D K Sharma, and
K K Pant, and
J N Sinha, and
K P Bhargava
December 1990,
British journal of pharmacology,
S Gurtu, and
D K Sharma, and
K K Pant, and
J N Sinha, and
K P Bhargava
October 1963,
The American journal of physiology,
S Gurtu, and
D K Sharma, and
K K Pant, and
J N Sinha, and
K P Bhargava
August 1991,
Brain research,
S Gurtu, and
D K Sharma, and
K K Pant, and
J N Sinha, and
K P Bhargava
January 1994,
Peptides,
S Gurtu, and
D K Sharma, and
K K Pant, and
J N Sinha, and
K P Bhargava
November 2007,
Hypertension (Dallas, Tex. : 1979),
S Gurtu, and
D K Sharma, and
K K Pant, and
J N Sinha, and
K P Bhargava
January 2002,
Autonomic neuroscience : basic & clinical,
S Gurtu, and
D K Sharma, and
K K Pant, and
J N Sinha, and
K P Bhargava
March 1992,
The American journal of physiology,
S Gurtu, and
D K Sharma, and
K K Pant, and
J N Sinha, and
K P Bhargava
January 1983,
Biomedica biochimica acta,
S Gurtu, and
D K Sharma, and
K K Pant, and
J N Sinha, and
K P Bhargava
January 1977,
Progress in brain research,
S Gurtu, and
D K Sharma, and
K K Pant, and
J N Sinha, and
K P Bhargava
May 1999,
Canadian journal of physiology and pharmacology,
