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2-Methylresorcinol (2-MR) was administered to groups of 40 male and 35 female Sprague-Dawley rats by admixture with the diets at levels of 0.1, 0.4, and 1.5% (see Part I; T.H. Re, R.F. Loehr, S.C. Rodriguez, C.E. Gilmore, and C.M. Burnett, 1986, Fundam. Appl. Toxicol. 7, 287-292). Following 90 days of exposure, 25 randomly selected females in each group were mated to untreated males in a teratology study in which exposure to 2-MR continued throughout the gestation period. After 20 weeks of exposure to 2-MR, 20 males per group were removed from the test diets containing 2-MR and were mated to untreated females in a dominant lethal study. Feeding 2-MR at levels of 0.4 and 1.5% in the diet was associated with a significant reduction in body weight gain. 2-MR was not teratogenic nor did it induce a dominant lethal effect under the conditions of this study.
T A Re, and
R F Loehr, and
S C Rodriguez, and
D E Rodwell, and
C M Burnett
May 1987,
Mutation research,
T A Re, and
R F Loehr, and
S C Rodriguez, and
D E Rodwell, and
C M Burnett
March 1980,
Ecotoxicology and environmental safety,
T A Re, and
R F Loehr, and
S C Rodriguez, and
D E Rodwell, and
C M Burnett
January 1976,
Food and cosmetics toxicology,
T A Re, and
R F Loehr, and
S C Rodriguez, and
D E Rodwell, and
C M Burnett
February 1973,
Food and cosmetics toxicology,
T A Re, and
R F Loehr, and
S C Rodriguez, and
D E Rodwell, and
C M Burnett
January 1983,
Fundamental and applied toxicology : official journal of the Society of Toxicology,
T A Re, and
R F Loehr, and
S C Rodriguez, and
D E Rodwell, and
C M Burnett
January 1993,
Journal of applied toxicology : JAT,
T A Re, and
R F Loehr, and
S C Rodriguez, and
D E Rodwell, and
C M Burnett
January 1996,
International journal of occupational medicine and environmental health,
T A Re, and
R F Loehr, and
S C Rodriguez, and
D E Rodwell, and
C M Burnett
April 1986,
Mutation research,
T A Re, and
R F Loehr, and
S C Rodriguez, and
D E Rodwell, and
C M Burnett
March 1984,
Toxicology letters,
T A Re, and
R F Loehr, and
S C Rodriguez, and
D E Rodwell, and
C M Burnett
June 1972,
Food and cosmetics toxicology,
