Biomaterial Database

Methionine, choline and sulfate interrelationships in the diet of weanling swine. 1986

T D Lovett, and M T Coffey, and R D Miles, and G E Combs

Experiments were conducted to examine the interrelationships between methionine, choline and inorganic sulfate in the diet of weanling pigs, and to evaluate the selenium (Se) status of pigs fed diets with or without supplemental sulfate. Two trials utilized 288 weanling (3-wk-old) pigs allotted to dietary treatment based on weight, sex and litter origin. There were six pigs/pen and three replicate pens/treatment in each trial. The basal corn-soybean meal diet was formulated to supply .55% sulfur amino acids and contained a choline and sulfur-free vitamin and mineral premix. Lysine was added to provide a total of 1.13% lysine. Seven additional treatments were formulated by substituting for corn .17% DL-methionine, .29% choline dihydrogen citrate or .25% Na2SO4 to create a 2(3) factorial arrangement of treatments. There were methionine X choline X sulfate interactions for average daily gain (P less than .001) and feed-to-gain ratio (F:G; P less than .05). Adding choline, methionine, Na2SO4 or choline plus methionine to the basal diet did not improve gains. However, when Na2SO4 plus methionine or Na2SO4 plus choline were added, daily gains were increased (P less than .05) and F:G was improved (P less than .1). Addition of all three supplements did not result in a further increase in gain. Pigs fed choline-supplemented diets had higher (P less than .01) hematocrit and tended (P = .07) to have increased hemoglobin concentration. There was no effect on serum triglycerides or alkaline phosphatase activity due to dietary treatment. The concentration of Se in muscle, liver, kidney and blood was not influenced by sulfate content of the diet.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D008715	Methionine	A sulfur-containing essential L-amino acid that is important in many body functions.	L-Methionine,Liquimeth,Methionine, L-Isomer,Pedameth,L-Isomer Methionine,Methionine, L Isomer
D001835	Body Weight	The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.	Body Weights,Weight, Body,Weights, Body
D002794	Choline	A basic constituent of lecithin that is found in many plants and animal organs. It is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism.	Bursine,Fagine,Vidine,2-Hydroxy-N,N,N-trimethylethanaminium,Choline Bitartrate,Choline Chloride,Choline Citrate,Choline Hydroxide,Choline O-Sulfate,Bitartrate, Choline,Chloride, Choline,Choline O Sulfate,Citrate, Choline,Hydroxide, Choline,O-Sulfate, Choline
D004032	Diet	Regular course of eating and drinking adopted by a person or animal.	Diets
D005260	Female		Females
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D012643	Selenium	An element with the atomic symbol Se, atomic number 34, and atomic weight 78.97. It is an essential micronutrient for mammals and other animals but is toxic in large amounts. Selenium protects intracellular structures against oxidative damage. It is an essential component of GLUTATHIONE PEROXIDASE.	Selenium-80,Selenium 80
D013431	Sulfates	Inorganic salts of sulfuric acid.	Sulfate,Sulfates, Inorganic,Inorganic Sulfates
D013552	Swine	Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA).	Phacochoerus,Pigs,Suidae,Warthogs,Wart Hogs,Hog, Wart,Hogs, Wart,Wart Hog