Three trials evaluated associative action of alfalfa in ammonia (NH3)-treated corn residue diets and(or) potential ruminal degradable protein X escape protein interactions. In trial 1, 128 crossbred steers (250 kg) were fed 0 or 3% NH3-treated residue diets replaced by 0, 15, 30 or 100% of alfalfa hay. Basal diets were formulated to contain adequate metabolizable and crude protein but were nearly devoid of ruminal degradable protein. Ammonia treatment increased (P less than .02) dry matter (DM) intake of residues. Pooled across residue treatment, intake increased linearly (P less than .01) with increased level of alfalfa. A residue treatment X level of alfalfa interaction (P less than .02) for daily gain resulted because the response to level of alfalfa was linear (P less than .01) for nontreated residues and quadratic (P less than .01) for NH3-treated residues. Similar responses (P less than or equal to .07) were found for efficiency of gain, indicating that addition of 15 or 30% alfalfa promoted greater associative action for combinations involving NH3-treated vs nontreated residues. In an in vitro trial (trial 2) with the same corn cob and alfalfa diets used in trial 1, NH3 treatment increased (P less than .01) in vitro DM disappearance and rate of cell wall digestion of corn cobs. Alfalfa had no effect on rate of nontreated cob cell wall digestion, but increased (P less than .01) the rate for NH3-treated cobs.(ABSTRACT TRUNCATED AT 250 WORDS)