Recent incidence and secular trends in Hodgkin's disease and its histologic subtypes. 1986

S L Glaser

Incidence data from national cancer surveys (1947, 1969-71, 1973-80) in selected regions of the United States were used to describe the epidemiology of Hodgkin's disease (HD) in whites over all regions by age, sex and Rye histologic subtype in the 1970s, and time trends for HD overall. Before 1971, rates increased in young adults, notably men, and in older persons. During the 1970s, rates in children were stable, but young adult rates were high and rose slightly, particularly among women; both trends reflected elevated incidence of Nodular Sclerosis, the only subtype with increasing rates. For adults over 40, rates of all subtypes declined after 1969-71. Thus HD incidence in this country is not static, even over the last decade. Rate stability in younger children may indicate disappearance of environmentally caused HD. Incidence declines for older persons suggest a cohort effect, depletion of young adult susceptibles, or improvements in diagnostic accuracy.

UI MeSH Term Description Entries
D008297 Male Males
D005260 Female Females
D006689 Hodgkin Disease A malignant disease characterized by progressive enlargement of the lymph nodes, spleen, and general lymphoid tissue. In the classical variant, giant usually multinucleate Hodgkin's and REED-STERNBERG CELLS are present; in the nodular lymphocyte predominant variant, lymphocytic and histiocytic cells are seen. Granuloma, Hodgkin,Granuloma, Malignant,Hodgkin Lymphoma,Lymphogranuloma, Malignant,Granuloma, Hodgkin's,Granuloma, Hodgkins,Hodgkin Lymphoma, Adult,Hodgkin's Disease,Hodgkin's Lymphoma,Hodgkins Disease,Lymphocyte Depletion Hodgkin's Lymphoma,Lymphocyte-Rich Classical Hodgkin's Lymphoma,Mixed Cellularity Hodgkin's Lymphoma,Nodular Lymphocyte-Predominant Hodgkin's Lymphoma,Nodular Sclerosing Hodgkin's Lymphoma,Adult Hodgkin Lymphoma,Disease, Hodgkin,Disease, Hodgkin's,Disease, Hodgkins,Hodgkin Granuloma,Hodgkin's Granuloma,Hodgkins Granuloma,Hodgkins Lymphoma,Lymphocyte Rich Classical Hodgkin's Lymphoma,Lymphogranulomas, Malignant,Lymphoma, Hodgkin,Lymphoma, Hodgkin's,Malignant Granuloma,Malignant Granulomas,Malignant Lymphogranuloma,Malignant Lymphogranulomas,Nodular Lymphocyte Predominant Hodgkin's Lymphoma
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000367 Age Factors Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time. Age Reporting,Age Factor,Factor, Age,Factors, Age
D014481 United States A country in NORTH AMERICA between CANADA and MEXICO.

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