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Purified peripheral blood T lymphocytes from normal donors were shown to help allogeneic tonsillar B cells to differentiate and secrete specific anti-SRBC antibody in vitro in a plaque-forming assay. Utilizing this system, a comparison was made between the allogeneic helper activity generated by the T cells of normal individuals and patients with various disease states. Allogeneic helper activity was absent when T lymphocytes from patients with CLL were used. Conversely, relatively normal allogeneic helper function was provided by T cells of patients with a variety of other disorders studied. Thus, a functional deficiency was identified in CLL patients in the subpopulation of regulatory T cells responsible for providing helper activity in allogeneic interactions.
N Chiorazzi, and
S M Fu, and
G Montazeri, and
H G Kunkel, and
K Rai, and
T Gee
January 1982,
Haematologica,
N Chiorazzi, and
S M Fu, and
G Montazeri, and
H G Kunkel, and
K Rai, and
T Gee
July 2006,
Leukemia & lymphoma,
N Chiorazzi, and
S M Fu, and
G Montazeri, and
H G Kunkel, and
K Rai, and
T Gee
January 2021,
Frontiers in oncology,
N Chiorazzi, and
S M Fu, and
G Montazeri, and
H G Kunkel, and
K Rai, and
T Gee
August 1986,
[Rinsho ketsueki] The Japanese journal of clinical hematology,
N Chiorazzi, and
S M Fu, and
G Montazeri, and
H G Kunkel, and
K Rai, and
T Gee
January 1983,
Haematologica,
N Chiorazzi, and
S M Fu, and
G Montazeri, and
H G Kunkel, and
K Rai, and
T Gee
October 1981,
Tumori,
N Chiorazzi, and
S M Fu, and
G Montazeri, and
H G Kunkel, and
K Rai, and
T Gee
September 1984,
Orvosi hetilap,
N Chiorazzi, and
S M Fu, and
G Montazeri, and
H G Kunkel, and
K Rai, and
T Gee
January 1984,
Eksperimental'naia onkologiia,
N Chiorazzi, and
S M Fu, and
G Montazeri, and
H G Kunkel, and
K Rai, and
T Gee
November 2019,
American journal of clinical pathology,
N Chiorazzi, and
S M Fu, and
G Montazeri, and
H G Kunkel, and
K Rai, and
T Gee
January 2015,
Leukemia & lymphoma,
