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Twenty-nine patients with inoperable non-small cell lung cancer were treated as out-patients with vindesine and mitomycin C. Eight patients had a complete response, and nine a partial response. Response was generally associated with either stable or improving ECOG and symptom scores. The incidence of serious side-effects was low--only two patients' white cell count fell below 3000 cells/mm2, only one patient's platelet count fell below 100,000 cells/mm2, and two patients developed vomiting associated with treatment. The combination of vindesine and mitomycin C appears to be effective in the treatment of inoperable non-small cell lung cancer. Side effects were generally well tolerated and allowed out-patient treatment.
J Main, and
R A Clark, and
A Hutcheon
May 1992,
The Medical journal of Australia,
J Main, and
R A Clark, and
A Hutcheon
April 1991,
Journal of clinical oncology : official journal of the American Society of Clinical Oncology,
J Main, and
R A Clark, and
A Hutcheon
August 1990,
Gan to kagaku ryoho. Cancer & chemotherapy,
J Main, and
R A Clark, and
A Hutcheon
February 1992,
American journal of clinical oncology,
J Main, and
R A Clark, and
A Hutcheon
August 1985,
Onkologie,
J Main, and
R A Clark, and
A Hutcheon
January 1993,
European journal of cancer (Oxford, England : 1990),
J Main, and
R A Clark, and
A Hutcheon
October 1991,
American journal of clinical oncology,
J Main, and
R A Clark, and
A Hutcheon
February 1990,
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J Main, and
R A Clark, and
A Hutcheon
January 1991,
Cancer chemotherapy and pharmacology,
J Main, and
R A Clark, and
A Hutcheon
September 1987,
Gan to kagaku ryoho. Cancer & chemotherapy,
