-transparent.png){kind=logo}
We prepared monoclonal antibodies against pancreatic cancer associated antigen (PCAA) from normal colonic mucosa (PCAAc) and prepared an assay system to detect the circulating PCAAc in sera. 200 patients with cancer including 85 pancreatic cancer and benign disease were compared with 40 normal healthy individuals. Diagnostic rate of pancreatic cancer was 64/85 (75%) but other malignancy also showed elevated PCAAc: 18/19 (94.7%) of hepatoma and 19/37 (51.4%) of gastric cancer. In pancreatitis, 8/17 (47.1%) showed elevated PCAAc. Compared with our previous reports of PCAA assay, these results indicated that diagnostic sensitivity of pancreatic cancer was increased but specificity of it was decreased.
T Kobayashi, and
T Shimano, and
M Tatsuta, and
K Shibata, and
M Naoi, and
T Mori
December 1984,
Clinica chimica acta; international journal of clinical chemistry,
T Kobayashi, and
T Shimano, and
M Tatsuta, and
K Shibata, and
M Naoi, and
T Mori
January 1983,
Annals of the New York Academy of Sciences,
T Kobayashi, and
T Shimano, and
M Tatsuta, and
K Shibata, and
M Naoi, and
T Mori
January 1990,
Digestion,
T Kobayashi, and
T Shimano, and
M Tatsuta, and
K Shibata, and
M Naoi, and
T Mori
October 1978,
Cancer research,
T Kobayashi, and
T Shimano, and
M Tatsuta, and
K Shibata, and
M Naoi, and
T Mori
January 1990,
Japanese journal of cancer research : Gann,
T Kobayashi, and
T Shimano, and
M Tatsuta, and
K Shibata, and
M Naoi, and
T Mori
April 1986,
Cancer research,
T Kobayashi, and
T Shimano, and
M Tatsuta, and
K Shibata, and
M Naoi, and
T Mori
October 1984,
Cancer research,
T Kobayashi, and
T Shimano, and
M Tatsuta, and
K Shibata, and
M Naoi, and
T Mori
February 1986,
The Tohoku journal of experimental medicine,
T Kobayashi, and
T Shimano, and
M Tatsuta, and
K Shibata, and
M Naoi, and
T Mori
February 1989,
International journal of cancer,
T Kobayashi, and
T Shimano, and
M Tatsuta, and
K Shibata, and
M Naoi, and
T Mori
October 1991,
Cancer research,
