Biomaterial Database

A genome assembly of the Yuma myotis bat, Myotis yumanensis. 2024

Joseph N Curti, and Devaughn Fraser, and Merly Escalona, and Colin W Fairbairn, and Samuel Sacco, and Ruta Sahasrabudhe, and Oanh Nguyen, and William Seligmann, and Peter H Sudmant, and Erin Toffelmier, and Juan Manuel Vazquez, and Robert Wayne, and H Bradley Shaffer, and Michael R Buchalski

Department of Ecology and Evolutionary Biology, University of California, Los Angeles (UCLA), Los Angeles, CA, United States.

The Yuma myotis bat (Myotis yumanensis) is a small vespertilionid bat and one of 52 species of new world Myotis bats in the subgenus Pizonyx. While M. yumanensis populations currently appear relatively stable, it is one of 12 bat species known or suspected to be susceptible to white-nose syndrome, the fungal disease causing declines in bat populations across North America. Only two of these 12 species have genome resources available, which limits the ability of resource managers to use genomic techniques to track the responses of bat populations to white-nose syndrome generally. Here we present the first de novo genome assembly for Yuma myotis, generated as a part of the California Conservation Genomics Project. The M. yumanensis genome was generated using a combination of PacBio HiFi long reads and Omni-C chromatin-proximity sequencing technology. This high-quality genome is one of the most complete bat assemblies available, with a contig N50 of 28.03 Mb, scaffold N50 of 99.14 Mb, and BUSCO completeness score of 93.7%. The Yuma myotis genome provides a high-quality resource that will aid in comparative genomic and evolutionary studies, as well as inform conservation management related to white-nose syndrome.