Ankle arthritis is a disabling disease pattern resulting in pain and dysfunction ultimately leading to a reduction in quality of life. Unlike more common arthritides of the knee and hip, ankle arthritis is unique in its presentation with an earlier onset of end-stage disease and an etiology, which is most-commonly posttraumatic in nature. Through continued research and design, improvements have continued to be made as newer generation implants are developed. This article discusses the considerations for revision total ankle replacement based on the current revision options and a treatment algorithm developed by the lead author.