Biomaterial Database

[Lithium salts in the treatment of cluster headache]. 1979

F Savoldi, and G Nappi, and G Bono

After analysing personal results and the data in the literature concerning the therapeutic effects of Lithium salts in cluster headache, the Authors discuss some of the pathogenetic problems related to this particular form of idiopathic headache. The results obtained seem very favourable however the therapeutic efficiency of Lithium salts, also observed in neuralgic-vasomotor syndromes (Charlin, Sluder) and in some forms of chronic headache, seems to indicate a relatively unspecific mechanism of action. The Authors suggest therefore an intervention in the stabilization of the membrane at the CNS level, with increasing efficiency of "antinociceptive" system.

UI	MeSH Term	Description	Entries
D008094	Lithium	An element in the alkali metals family. It has the atomic symbol Li, atomic number 3, and atomic weight [6.938; 6.997]. Salts of lithium are used in treating BIPOLAR DISORDER.	Lithium-7,Lithium 7
D008297	Male		Males
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D003027	Cluster Headache	A primary headache disorder that is characterized by severe, strictly unilateral PAIN which is orbital, supraorbital, temporal or in any combination of these sites, lasting 15-180 min. occurring 1 to 8 times a day. The attacks are associated with one or more of the following, all of which are ipsilateral: conjunctival injection, lacrimation, nasal congestion, rhinorrhea, facial SWEATING, eyelid EDEMA, and miosis. (International Classification of Headache Disorders, 2nd ed. Cephalalgia 2004: suppl 1)	Ciliary Neuralgia,Headache, Cluster,Histamine Cephalgia,Horton Syndrome,Neuralgic Migraine,Atypical Cluster Headache,Chronic Cluster Headache,Cluster Headache Syndrome,Episodic Cluster Headache,Horton's Syndrome,Atypical Cluster Headaches,Cephalgia, Histamine,Cephalgias, Histamine,Chronic Cluster Headaches,Ciliary Neuralgias,Cluster Headache Syndromes,Cluster Headache, Atypical,Cluster Headache, Chronic,Cluster Headache, Episodic,Cluster Headaches,Cluster Headaches, Atypical,Cluster Headaches, Chronic,Cluster Headaches, Episodic,Episodic Cluster Headaches,Headache Syndrome, Cluster,Headache Syndromes, Cluster,Headache, Atypical Cluster,Headache, Chronic Cluster,Headache, Episodic Cluster,Headaches, Atypical Cluster,Headaches, Chronic Cluster,Headaches, Cluster,Headaches, Episodic Cluster,Histamine Cephalgias,Hortons Syndrome,Migraine, Neuralgic,Migraines, Neuralgic,Neuralgia, Ciliary,Neuralgias, Ciliary,Neuralgic Migraines,Syndrome, Cluster Headache,Syndrome, Horton,Syndrome, Horton's,Syndromes, Cluster Headache
D004341	Drug Evaluation	Any process by which toxicity, metabolism, absorption, elimination, preferred route of administration, safe dosage range, etc., for a drug or group of drugs is determined through clinical assessment in humans or veterinary animals.	Evaluation Studies, Drug,Drug Evaluation Studies,Drug Evaluation Study,Drug Evaluations,Evaluation Study, Drug,Evaluation, Drug,Evaluations, Drug,Studies, Drug Evaluation,Study, Drug Evaluation
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults
D000368	Aged	A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available.	Elderly
D014653	Vascular Headaches	Secondary headache disorders attributed to a variety of cranial or cervical vascular disorders, such as BRAIN ISCHEMIA; INTRACRANIAL HEMORRHAGES; and CENTRAL NERVOUS SYSTEM VASCULAR MALFORMATIONS.	Cephalgia, Vascular,Headache, Vascular,Vascular Headache,Cephalgias, Vascular,Headaches, Vascular,Vascular Cephalgia,Vascular Cephalgias