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A positive CDC B-lymphocyte XM is not deleterious to long-term graft outcome. A positive unfractionated CDC XM is not a contraindication to transplantation if the positive crossmatch is due entirely to anti-B-lymphocyte antibody. B-lymphocyte autoantibodies are common in hemodialysis patients, but may account for only a minority of positive B-lymphocyte XMs.
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