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Retinal capillary basement membrane damage was demonstrated over a relatively short time period (two to three months) by feeding a diet containing high amounts of sucrose to spontaneously hypertensive rats (SHR) and their normotensive controls, Wistar Kyoto rats (WKY). Similar changes did not occur in SHR and WKY on a high starch diet. The early damage to the capillaries consisted of thickening of capillary basement membranes, loss of homogeneity, and inclusions containing debris. Previous studies on sucrose-induced eye lesions have reported chronic pathological changes only after prolonged periods of heavy sucrose ingestion, usually exceeding one year. Accordingly, the temporally foreshortened experimental pathogenesis offered by the SHR/WKY model allowed us to examine early changes in sucrose-induced vascular eye lesions.
N S More, and
N A Rao, and
H G Preuss
August 2005,
Peptides,
N S More, and
N A Rao, and
H G Preuss
December 2020,
Behavioural processes,
N S More, and
N A Rao, and
H G Preuss
September 1996,
Physiology & behavior,
N S More, and
N A Rao, and
H G Preuss
October 1982,
The Journal of pharmacology and experimental therapeutics,
N S More, and
N A Rao, and
H G Preuss
July 1991,
Pharmaceutical research,
N S More, and
N A Rao, and
H G Preuss
December 1986,
Biochemical and biophysical research communications,
N S More, and
N A Rao, and
H G Preuss
January 1987,
Biomedica biochimica acta,
N S More, and
N A Rao, and
H G Preuss
February 1983,
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.),
N S More, and
N A Rao, and
H G Preuss
January 1990,
Progress in clinical and biological research,
N S More, and
N A Rao, and
H G Preuss
May 2019,
Behavioural brain research,
