-transparent.png){kind=logo}
A description is given of two patients with peculiar multiple skin eruptions, asymptomatic generalized lymphadenopathy, and polyclonal hypergammaglobulinemia. Both patients were admitted to our hospital for further evaluation of an increased erythrocyte sedimentation rate and hypergammaglobulinemia discovered during routine medical examinations. Despite various investigations, the underlying disease causing the hypergammaglobulinemia was not found. Histologic examination disclosed dense perivascular infiltration of plasma cells in the dermis. In the lymph nodes, considerable plasma cell infiltration was found from the cortex to the medulla. These plasma cells were mature and showed no cellular atypism. The association of peculiar multiple skin eruptions, lymphadenopathy, and polyclonal hypergammaglobulinemia, which we have called "systemic plasmacytosis," signifies a new syndrome that can be differentiated from diseases reported previously.
S Watanabe, and
K Ohara, and
A Kukita, and
S Mori
December 1983,
Nihon Hifuka Gakkai zasshi. The Japanese journal of dermatology,
S Watanabe, and
K Ohara, and
A Kukita, and
S Mori
October 1980,
The Journal of dermatology,
S Watanabe, and
K Ohara, and
A Kukita, and
S Mori
March 1992,
[Rinsho ketsueki] The Japanese journal of clinical hematology,
S Watanabe, and
K Ohara, and
A Kukita, and
S Mori
June 1997,
The American Journal of dermatopathology,
S Watanabe, and
K Ohara, and
A Kukita, and
S Mori
July 1973,
The American journal of medicine,
S Watanabe, and
K Ohara, and
A Kukita, and
S Mori
May 1987,
Nihon Kyobu Shikkan Gakkai zasshi,
S Watanabe, and
K Ohara, and
A Kukita, and
S Mori
March 1983,
Deutsche medizinische Wochenschrift (1946),
S Watanabe, and
K Ohara, and
A Kukita, and
S Mori
April 1984,
Cancer,
S Watanabe, and
K Ohara, and
A Kukita, and
S Mori
July 1992,
The British journal of dermatology,
S Watanabe, and
K Ohara, and
A Kukita, and
S Mori
April 1992,
Internal medicine (Tokyo, Japan),
