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Antibody persistence was measured in 39 children in an open community 12-13 years after immunization against measles with further attenuated live vaccine, Biken CAM. Serum samples of the children taken every two or three years after vaccination had higher, lower, or the same HI antibody titers as those in samples taken 6 weeks after vaccination. These differences reflected a decrease in the titer in some children and subclinical natural reinfection in others. However, all the children still retained detectable antibody in 12 or 13 years after vaccination, indicating long-term persistence of immunity after immunization with Biken CAM vaccine. For evaluation of the protective efficacy of the vaccine, matched controls were studied during the same period. Serological examination revealed that 97.5% of the controls were infected with measles and contracted the disease. In contrast, none of the vaccinees developed clinical infection after close contact with measles patients.
S Isomura, and
T Morishima, and
K Nishikawa, and
N Hanada, and
M Rahman, and
M Terashima, and
S Kido, and
S Ueda, and
M Takahashi
June 1982,
Biken journal,
S Isomura, and
T Morishima, and
K Nishikawa, and
N Hanada, and
M Rahman, and
M Terashima, and
S Kido, and
S Ueda, and
M Takahashi
September 1970,
Biken journal,
S Isomura, and
T Morishima, and
K Nishikawa, and
N Hanada, and
M Rahman, and
M Terashima, and
S Kido, and
S Ueda, and
M Takahashi
September 1970,
Biken journal,
S Isomura, and
T Morishima, and
K Nishikawa, and
N Hanada, and
M Rahman, and
M Terashima, and
S Kido, and
S Ueda, and
M Takahashi
August 2000,
Revista de saude publica,
S Isomura, and
T Morishima, and
K Nishikawa, and
N Hanada, and
M Rahman, and
M Terashima, and
S Kido, and
S Ueda, and
M Takahashi
January 1965,
Archiv fur die gesamte Virusforschung,
S Isomura, and
T Morishima, and
K Nishikawa, and
N Hanada, and
M Rahman, and
M Terashima, and
S Kido, and
S Ueda, and
M Takahashi
September 1970,
Biken journal,
S Isomura, and
T Morishima, and
K Nishikawa, and
N Hanada, and
M Rahman, and
M Terashima, and
S Kido, and
S Ueda, and
M Takahashi
March 1971,
Biken journal,
S Isomura, and
T Morishima, and
K Nishikawa, and
N Hanada, and
M Rahman, and
M Terashima, and
S Kido, and
S Ueda, and
M Takahashi
January 1964,
Paediatrica Indonesiana,
S Isomura, and
T Morishima, and
K Nishikawa, and
N Hanada, and
M Rahman, and
M Terashima, and
S Kido, and
S Ueda, and
M Takahashi
January 1967,
Progress in immunobiological standardization,
S Isomura, and
T Morishima, and
K Nishikawa, and
N Hanada, and
M Rahman, and
M Terashima, and
S Kido, and
S Ueda, and
M Takahashi
June 1963,
Pediatrics,
