-transparent.png){kind=logo}
The relative half-life of ornithine transcarbamylase from rat liver has been determined using the double isotope technique and affinity chromatography. The calculated half-life (6-9 days) is similar to that of mitochondria and of the other mitochondrial enzyme of the urea cycle, carbamoyl-phosphate synthase. Therefore, both mitochondrial urea cycle enzymes are most probably degraded mainly via the lysosomal (autophagic) pathway of mitochondrial protein degradation.
Related Publications
R Wallace, and
E Knecht, and
S Grisolía
April 1977,
Pediatric research,
R Wallace, and
E Knecht, and
S Grisolía
January 1981,
Biochemical and biophysical research communications,
R Wallace, and
E Knecht, and
S Grisolía
November 1982,
Molecular and cellular biochemistry,
R Wallace, and
E Knecht, and
S Grisolía
October 1979,
The Journal of biological chemistry,
R Wallace, and
E Knecht, and
S Grisolía
January 1968,
Physiologia Bohemoslovaca,
R Wallace, and
E Knecht, and
S Grisolía
January 1996,
The Journal of nutrition,
R Wallace, and
E Knecht, and
S Grisolía
December 1970,
Paediatria Universitatis Tokyo,
R Wallace, and
E Knecht, and
S Grisolía
March 1994,
Archives of biochemistry and biophysics,
R Wallace, and
E Knecht, and
S Grisolía
October 1990,
Protein engineering,
R Wallace, and
E Knecht, and
S Grisolía
June 2011,
Pediatric transplantation,
