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Fifteen patients operated on for medullary thyroid carcinoma with elevated postoperative serum calcitonin (CT) levels underwent serial measurements of serum CT and carcinoembryonic antigen (CEA) levels. Both CT and CEA levels showed an exponential increase in 12 patients and a slight decrease in three. CEA levels manifested less fluctuation than CT levels. The doubling time of these tumor marker levels calculated from the regression line in each patient showed a strong correlation with three-year survival, recurrence within five years, and the time interval between surgery and recurrence of the tumor, allowing quantitative prediction of the prognosis. However, the doubling time of CEA was longer than that of CT in most patients.
A Miyauchi, and
T Onishi, and
F Matsuzuka, and
K Hirai, and
K Kuma, and
S Takai, and
K Nakamoto, and
K Nakamura, and
S Nanjo, and
M Maeda
November 2005,
The Journal of clinical endocrinology and metabolism,
A Miyauchi, and
T Onishi, and
F Matsuzuka, and
K Hirai, and
K Kuma, and
S Takai, and
K Nakamoto, and
K Nakamura, and
S Nanjo, and
M Maeda
January 1987,
Henry Ford Hospital medical journal,
A Miyauchi, and
T Onishi, and
F Matsuzuka, and
K Hirai, and
K Kuma, and
S Takai, and
K Nakamoto, and
K Nakamura, and
S Nanjo, and
M Maeda
March 2012,
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association,
A Miyauchi, and
T Onishi, and
F Matsuzuka, and
K Hirai, and
K Kuma, and
S Takai, and
K Nakamoto, and
K Nakamura, and
S Nanjo, and
M Maeda
February 2008,
European journal of endocrinology,
A Miyauchi, and
T Onishi, and
F Matsuzuka, and
K Hirai, and
K Kuma, and
S Takai, and
K Nakamoto, and
K Nakamura, and
S Nanjo, and
M Maeda
April 2010,
Clinical endocrinology,
A Miyauchi, and
T Onishi, and
F Matsuzuka, and
K Hirai, and
K Kuma, and
S Takai, and
K Nakamoto, and
K Nakamura, and
S Nanjo, and
M Maeda
June 2004,
Thyroid : official journal of the American Thyroid Association,
A Miyauchi, and
T Onishi, and
F Matsuzuka, and
K Hirai, and
K Kuma, and
S Takai, and
K Nakamoto, and
K Nakamura, and
S Nanjo, and
M Maeda
November 2004,
Thyroid : official journal of the American Thyroid Association,
A Miyauchi, and
T Onishi, and
F Matsuzuka, and
K Hirai, and
K Kuma, and
S Takai, and
K Nakamoto, and
K Nakamura, and
S Nanjo, and
M Maeda
March 1977,
Biomedicine / [publiee pour l'A.A.I.C.I.G.],
A Miyauchi, and
T Onishi, and
F Matsuzuka, and
K Hirai, and
K Kuma, and
S Takai, and
K Nakamoto, and
K Nakamura, and
S Nanjo, and
M Maeda
May 1984,
The Journal of clinical endocrinology and metabolism,
A Miyauchi, and
T Onishi, and
F Matsuzuka, and
K Hirai, and
K Kuma, and
S Takai, and
K Nakamoto, and
K Nakamura, and
S Nanjo, and
M Maeda
March 1983,
Cancer,
