[Risk of cancer in women occupationally exposed to asbestos dust]. 1986

N Szeszenia-Dabrowska, and U Wilczyńska, and W Szymczak

In order to estimate the risk of death due to cancer in those occupationally exposed to asbestos dust, 1190 women--workers of an asbestos producing plant--employed for at least 3 months during 1945-1973, were examined. The cohort availability for 31 December 1981 was 89.6%. The risk was analyzed basing on the standardized mortality ratio (SMR) calculated by the man-years method. The reference group was that of the general population of women in Poland. In the test cohort, 136 deaths occurred (SMR = 93.3), in this 46 were caused by malignant tumours (SMR = 162.0), 25 by malignant tumours of the digestive organs and peritoneum (SMR = 226.9), 13 by malignant tumours of the liver and pancreas (SMR = 360.9). The mortality due to the above mentioned causes was significantly higher than that of the general population. In the subcohort of women employed during 1945-1955 selected for the very high concentration of asbestos dust 95 deaths occurred in this period (SMR = 111.1). Significantly higher than in the reference population was mortality of: malignant tumours totally (32 deaths, SMR = 206.1), malignant tumours of the digestive organs and peritoneum (20 deaths. SMR = 311.0), and malignant tumours of the liver and pancreas (12 deaths, SMR = 541.5).

UI MeSH Term Description Entries
D009784 Occupational Diseases Diseases caused by factors involved in one's employment. Diseases, Occupational,Occupational Illnesses,Disease, Occupational,Illnesse, Occupational,Illnesses, Occupational,Occupational Disease,Occupational Illnesse
D011044 Poland A country in central Europe, east of Germany. The capital is Warsaw. Polish People's Republic,Republic of Poland
D012142 Respiratory Tract Neoplasms Tumors or cancer of the RESPIRATORY SYSTEM. Respiratory Neoplasms,Respiratory System Neoplasms,Neoplasm, Respiratory,Neoplasm, Respiratory System,Neoplasm, Respiratory Tract,Respiratory Neoplasm,Respiratory System Neoplasm,Respiratory Tract Neoplasm
D004067 Digestive System Neoplasms Tumors or cancer of the DIGESTIVE SYSTEM. Cancer of Digestive System,Digestive System Cancer,Cancer of the Digestive System,Neoplasms, Digestive System,Cancer, Digestive System,Cancers, Digestive System,Digestive System Cancers,Digestive System Neoplasm,Neoplasm, Digestive System
D004391 Dust Earth or other matter in fine, dry particles. (Random House Unabridged Dictionary, 2d ed) House Dust,Housedust,Dust, House
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D001194 Asbestos Asbestos. Fibrous incombustible mineral composed of magnesium and calcium silicates with or without other elements. It is relatively inert chemically and used in thermal insulation and fireproofing. Inhalation of dust causes asbestosis and later lung and gastrointestinal neoplasms.
D012306 Risk The probability that an event will occur. It encompasses a variety of measures of the probability of a generally unfavorable outcome. Relative Risk,Relative Risks,Risk, Relative,Risks,Risks, Relative

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