Clinical significance of Nosocomiicoccus ampullae isolated from blood cultures. 2023

Victoria L Campodónico, and Tsigereda Tekle, and Yehudit Bergman, and Jennifer Lu, and Emily Gisriel, and Mark Romagnoli, and Dimitrios Bourdas, and Ann Hanlon, and Carmila Manuel, and Romney Humphries, and Patricia J Simner, and Karen C Carroll
Division of Medical Microbiology, Department of Pathology, The Johns Hopkins University School of Medicine , Baltimore, Maryland, USA.

Nosocomiicoccus species are recently described as members of the Staphylococcaceae family. With their inclusion in commercial matrix-assisted laser desorption/ionization-time of flight mass spectrometry databases, Nosocomiicoccus species can now be identified when Gram-positive cocci in clusters are detected in positive blood cultures. However, their clinical significance is not known, making it difficult for the clinical microbiology laboratory to decide the extent of work-up. Based on our study, Nosocomiicoccus species demonstrate low pathogenicity and opportunistic potential. If isolated from a single blood culture set, limited work-up should be performed to an extent similar to other possible blood culture contaminants.

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