Biomaterial Database

Using Compression Therapy to Treat Bilateral Lower Limb Edema in Patients with Lung Cancer: A Case Series. 2023

Naomi Kayauchi, and Takako Nagatsu, and Hiroaki Satoh

In the College of Nursing, Ibaraki Christian University, Hitachi, Ibaraki, Japan, Naomi Kayauchi, MSN, RN, is Assistant Professor and Takako Nagatsu, MSN, RN, is Associate Professor. Hiroaki Satoh, MD, PhD, is Professor, Mito Medical Center, University of Tsukuba, Mito, Ibaraki. The authors have disclosed no financial relationships related to this article. Submitted August 22, 2022; accepted in revised form December 22, 2022.

Although rare, marked bilateral leg edema (BLE) can occur in patients with lung cancer. Systemic therapy for the underlying disease is important, but adjunct therapy might also be helpful. In this case series, the authors report on treating BLE in patients with lung cancer with compression therapy using elastic stockings and bandages. From April 2013 to March 2022, the authors conducted a retrospective survey of seven patients who developed marked BLE and received compression therapy. They evaluated effects based on improvements in subjective symptoms as well as objective findings 2 months after the start of the therapy. The bandage therapy was useful in patients who were driver-gene negative, but it was not effective in those who already had "progressive disease" with specific agents for their driver genes. No adverse events were observed. Compression therapy, even when attached or detached by nonmedical personnel, may provide favorable effects and should be considered as an adjunct treatment option in this population, in addition to effective systemic cancer therapy. These results indicate that a prospective clinical trial would be worthwhile.

UI	MeSH Term	Description	Entries
D008175	Lung Neoplasms	Tumors or cancer of the LUNG.	Cancer of Lung,Lung Cancer,Pulmonary Cancer,Pulmonary Neoplasms,Cancer of the Lung,Neoplasms, Lung,Neoplasms, Pulmonary,Cancer, Lung,Cancer, Pulmonary,Cancers, Lung,Cancers, Pulmonary,Lung Cancers,Lung Neoplasm,Neoplasm, Lung,Neoplasm, Pulmonary,Pulmonary Cancers,Pulmonary Neoplasm
D011446	Prospective Studies	Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.	Prospective Study,Studies, Prospective,Study, Prospective
D004487	Edema	Abnormal fluid accumulation in TISSUES or body cavities. Most cases of edema are present under the SKIN in SUBCUTANEOUS TISSUE.	Dropsy,Hydrops,Anasarca
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D012189	Retrospective Studies	Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.	Retrospective Study,Studies, Retrospective,Study, Retrospective
D053828	Stockings, Compression	Tight coverings for the foot and leg that are worn to aid circulation in the legs, and prevent the formation of EDEMA and DEEP VEIN THROMBOSIS. PNEUMATIC COMPRESSION STOCKINGS serve a similar purpose especially for bedridden patients, and following surgery.	Compression Stockings,Elastic Stockings,Stockings, Elastic,Compression Stocking,Elastic Stocking,Stocking, Compression,Stocking, Elastic
D058128	Compression Bandages	Strips of elastic material used to apply pressure to body parts to control EDEMA and aid circulation.	Compression Bandage,Compression Wraps,Elastic Bandages,Elastic Compression Wraps,Bandage, Compression,Bandage, Elastic,Bandages, Compression,Bandages, Elastic,Compression Wrap,Compression Wrap, Elastic,Compression Wraps, Elastic,Elastic Bandage,Elastic Compression Wrap,Wrap, Compression,Wrap, Elastic Compression,Wraps, Compression,Wraps, Elastic Compression
D035002	Lower Extremity	The region of the lower limb in animals, extending from the gluteal region to the FOOT, and including the BUTTOCKS; HIP; and LEG.	Extremity, Lower,Lower Limb,Membrum inferius,Extremities, Lower,Limb, Lower,Limbs, Lower,Lower Extremities,Lower Limbs