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In this prospective study 20 newly diagnosed patients with definite or classical rheumatoid arthritis were followed with serial measurements of serum ferritin and erythrocyte-free protoporphyrin at the beginning of the trial and at 3 and 6 months. The values were correlated with clinical disease activity ad with various laboratory parameters. It was shown that free erythrocyte protoporphyrin has a constant negative correlation with erythrocyte haemoglobin concentration independent of disease activity, while serum ferritin behaves like an acute phase protein. Initial serum ferritin or free erythrocyte protoporphyrin values or their early changes appeared to have no prognostic value as evaluated by the development of new erosions or by the response of the patient to the therapy.
P Hannonen, and
T Möttönen, and
M Oka
January 1977,
The American journal of the medical sciences,
P Hannonen, and
T Möttönen, and
M Oka
January 1989,
International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition,
P Hannonen, and
T Möttönen, and
M Oka
January 1989,
The Journal of laboratory and clinical medicine,
P Hannonen, and
T Möttönen, and
M Oka
January 1983,
Panminerva medica,
P Hannonen, and
T Möttönen, and
M Oka
July 1983,
The American journal of clinical nutrition,
P Hannonen, and
T Möttönen, and
M Oka
July 1950,
The Journal of clinical investigation,
P Hannonen, and
T Möttönen, and
M Oka
May 1978,
Acta paediatrica Scandinavica,
P Hannonen, and
T Möttönen, and
M Oka
January 1976,
British medical journal,
P Hannonen, and
T Möttönen, and
M Oka
January 1983,
Archives of environmental health,
P Hannonen, and
T Möttönen, and
M Oka
January 1977,
The Journal of rheumatology,
