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Synthesis of 1,2-Disubstituted Adamantane Derivatives by Construction of the Adamantane Framework. 2023

Matthew Todd, and Radim Hrdina
Department of Organic Chemistry, Faculty of Science, Charles University, Hlavova 8, 12043 Praha, Czech Republic.

This review summarizes achievements in the synthesis of 1,2-disubstituted adamantane derivatives by the construction of the tricyclic framework either by total synthesis or by ring expansion/contraction reactions of corresponding adamantane homologues. It is intended to complement reviews focusing on the preparation of 1,2-disubstituted derivatives by C-H functionalization methods.

UI MeSH Term Description Entries

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