-transparent.png){kind=logo}
A human liver cDNA library was screened by colony hybridization with a rat liver arginase cDNA. The number of positive clones detected was in agreement with the estimated abundance of arginase message in liver, and the identities of several of these clones were verified by hybrid-select translation, immunoprecipitation, and competition by purified arginase. The largest of these human liver arginase cDNAs was then used to detect arginase message on northern blots at levels consistent with the activities of liver arginase in the tissues and cells studied. The absence of a hybridization signal with mRNA from a cell line expressing only human kidney arginase demonstrated the lack of homology between the two human arginase genes and indicated considerable evolutionary divergence between these two loci.
G J Dizikes, and
W W Grody, and
R M Kern, and
S D Cederbaum
January 1987,
Proceedings of the National Academy of Sciences of the United States of America,
G J Dizikes, and
W W Grody, and
R M Kern, and
S D Cederbaum
February 1990,
Genomics,
G J Dizikes, and
W W Grody, and
R M Kern, and
S D Cederbaum
August 1992,
Biochemical and biophysical research communications,
G J Dizikes, and
W W Grody, and
R M Kern, and
S D Cederbaum
June 1988,
Biochemical medicine and metabolic biology,
G J Dizikes, and
W W Grody, and
R M Kern, and
S D Cederbaum
January 1989,
Pharmacological research,
G J Dizikes, and
W W Grody, and
R M Kern, and
S D Cederbaum
January 1972,
European journal of biochemistry,
G J Dizikes, and
W W Grody, and
R M Kern, and
S D Cederbaum
October 1985,
Proceedings of the National Academy of Sciences of the United States of America,
G J Dizikes, and
W W Grody, and
R M Kern, and
S D Cederbaum
July 1985,
FEBS letters,
G J Dizikes, and
W W Grody, and
R M Kern, and
S D Cederbaum
February 1987,
Biochemical and biophysical research communications,
G J Dizikes, and
W W Grody, and
R M Kern, and
S D Cederbaum
February 2002,
Journal of neuro-oncology,
