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Oral doses of either iopronic acid (4.5 g Oravue, Squibb) or iopanoic acid (3 g Telepaque, Winthrop) were given to 98 patients requiring cholecystography. Radiographs were taken 13 to 16 hours after treatment showed good to excellent gallbladder opacification in 44 percent of patients after the first dose of iopronic acid and in an additional 29 percent after a second dose. Similar opacification occurred in 42 percent of patients after the first dose of iopanoic acid and in 34 percent after a second dose. Drug-related abnormalities in blood and urine tests occurred about equally in both groups and one patient in each group exhibited a clinically adverse reaction (diarrhea). Thus, the performance (radiographic efficacy and drug safety) of the new contrast agent, iopronic acid, was similar to a widely used drug, iopanoic acid.
L Hedlund, and
C E Putman, and
M Burrell
January 1980,
Radiology,
L Hedlund, and
C E Putman, and
M Burrell
January 1982,
Investigative radiology,
L Hedlund, and
C E Putman, and
M Burrell
May 1978,
AJR. American journal of roentgenology,
L Hedlund, and
C E Putman, and
M Burrell
January 1974,
The New England journal of medicine,
L Hedlund, and
C E Putman, and
M Burrell
September 1976,
Il Farmaco; edizione pratica,
L Hedlund, and
C E Putman, and
M Burrell
August 1976,
Il Farmaco; edizione pratica,
L Hedlund, and
C E Putman, and
M Burrell
December 1955,
Journal of the American Medical Association,
L Hedlund, and
C E Putman, and
M Burrell
November 1978,
La Radiologia medica,
L Hedlund, and
C E Putman, and
M Burrell
February 1981,
Clinical toxicology,
L Hedlund, and
C E Putman, and
M Burrell
March 1982,
Die Medizinische Welt,
