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Chondrosarcoma secondary to hereditary multiple osteochondromas with spinal cord compression: A case report and systematic review. 2023
José Elmano Silva, and
Gabriel de Almeida Monteiro, and
Stefanie Torres E Silva, and
Gabriel Marinheiro Dos Santos Bezerra, and
Joaquim Francisco Cavalcante-Neto, and
Diego de Aragão Bezerra, and
Janssen Loiola Melo Vasconcelos, and
Paulo Roberto Lacerda Leal
Department of Neurosurgery, Federal University of Ceará, Sobral, Ceará, Brazil.
Hereditary multiple osteochondromas (HMOs) are a rare genetic disorder characterized by the formation of multiple benign osteochondromas that can undergo malignant transformation into chondrosarcoma. A 24-year-old male with a history of HMO and osteochondroma surgery 4 years ago, presented with back pain and paresthesias. The magnetic resonance showed a right paravertebral infiltrating mass at the T12-L1 level causing spinal cord compression. Following en bloc resection of the tumor, the patient's symptoms/ signs resolved. The final pathological diagnosis was consistent with a chondrosarcoma. Chondrosarcomas secondary to HMO with spinal cord compression are rare. These patients often presenting with significant myelopathy/cord compression should undergo gross total resection where feasible to achieve the best outcomes.
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