Bacteriolytic activity of lysozyme in the nasal mucosa. 1986

M Tachibana, and H Morioka, and M Machino, and O Mizukoshi

During an experiment to study the localization of the lysozyme in the nasal mucosa of humans by the protein A-gold technique, we observed the accumulation of lysozymes around bacteria possibly causing bacteriolysis. The lysozyme, therefore, seems to play a preventive role against some kind of bacterial infection in the nasal mucosa in situ.

UI MeSH Term Description Entries
D009113 Muramidase A basic enzyme that is present in saliva, tears, egg white, and many animal fluids. It functions as an antibacterial agent. The enzyme catalyzes the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrin. EC 3.2.1.17. Lysozyme,Leftose,N-Acetylmuramide Glycanhydrolase,Glycanhydrolase, N-Acetylmuramide,N Acetylmuramide Glycanhydrolase
D009297 Nasal Mucosa The mucous lining of the NASAL CAVITY, including lining of the nostril (vestibule) and the OLFACTORY MUCOSA. Nasal mucosa consists of ciliated cells, GOBLET CELLS, brush cells, small granule cells, basal cells (STEM CELLS) and glands containing both mucous and serous cells. Nasal Epithelium,Schneiderian Membrane,Epithelium, Nasal,Membrane, Schneiderian,Mucosa, Nasal
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D001433 Bacteriolysis Rupture of bacterial cells due to mechanical force, chemical action, or the lytic growth of BACTERIOPHAGES. Bacteriolyses

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