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In vitro activity of delafloxacin against anaerobic bacteria compared with other antimicrobials. 2023
Fernando Cobo, and
Ana Franco-Acosta, and
Lina Martín-Hita, and
Javier Rodríguez-Granger, and
Antonio Sampedro-Martínez, and
Juan Antonio Reguera-Márquez, and
José María Navarro-Marí
Department of Microbiology and Instituto de Investigación Biosanitaria Ibs.GRANADA, University Hospital Virgen de las Nieves, Granada, Spain. Electronic address: fernando.cobo.sspa@juntadeandalucia.es.
The aim of this study was to describe the in vitro activity of delafloxacin against 230 anaerobic isolates and compare it with the activity of other antimicrobials used against infections caused by anaerobic microorganisms. Minimal inhibitory concentrations (MICs) were lower for delafloxacin than for all other antibiotics tested with the exception of piperacillin-tazobactam and meropenem against Gram-positive anaerobic cocci. Only two (0.8 %) isolates of Bacteroides spp. showed a MIC ≥4 μg/mL. With some exceptions, the present results show lower MICs for delafloxacin in comparison to the other antibiotics used against anaerobes.
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