-transparent.png){kind=logo}
The mutant RP4ts12, derived from the R-factor RP4 and thermosensitive in replication, is incorporated into the chromosome A3dna(ts) of E. coli K12, thus suppressing dnaA mutation. The integration of this factor into the chromosome leads to the formation of Hfr strains of two types: the strains of the first type transfer plasmid markers to recipient cells earlier than to chromosomal ones; the strains of the second type transfer plasmid markers to recipient cells after chromosomal ones. During conjugation the R-factor integrated into the chromosome dissociates from chromosomal DNA introduced into the recipient cell and becomes autonomous.
Related Publications
S P Smirnov, and
V N Danilevich, and
E I Golub
July 1979,
Plasmid,
S P Smirnov, and
V N Danilevich, and
E I Golub
April 1978,
Antibiotiki,
S P Smirnov, and
V N Danilevich, and
E I Golub
February 1982,
Antibiotiki,
S P Smirnov, and
V N Danilevich, and
E I Golub
October 1983,
Genetika,
S P Smirnov, and
V N Danilevich, and
E I Golub
October 1967,
Proceedings of the National Academy of Sciences of the United States of America,
S P Smirnov, and
V N Danilevich, and
E I Golub
January 1968,
Cold Spring Harbor symposia on quantitative biology,
S P Smirnov, and
V N Danilevich, and
E I Golub
January 1971,
Annales de l'Institut Pasteur de Lille,
S P Smirnov, and
V N Danilevich, and
E I Golub
September 1969,
Genetics,
S P Smirnov, and
V N Danilevich, and
E I Golub
January 1972,
Molecular & general genetics : MGG,
S P Smirnov, and
V N Danilevich, and
E I Golub
April 1971,
Journal of bacteriology,
