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Effective control of a recurrent malignant pleural effusion can greatly improve the quality of life of the cancer patient. At least a dozen different techniques have been advocated for controlling this common complication of malignant disease. The present review collects and examines the clinical results of all techniques designed to treat this problem. The pathophysiology and diagnostic evaluation of the effusion are also discussed. On the basis of comparisons involving effectiveness, morbidity, and convenience, we recommend intrapleurally administered tetracycline with thoracostomy drainage as the technique of choice. Instillation of a talc suspension with thoracostomy drainage is also a safe and effective technique and should be employed when tetracycline fails or is contraindicated.
E H Austin, and
M W Flye
January 1969,
Thorax,
E H Austin, and
M W Flye
May 2010,
Journal of vascular and interventional radiology : JVIR,
E H Austin, and
M W Flye
January 2003,
Pneumonologia i alergologia polska,
E H Austin, and
M W Flye
February 1989,
Gan to kagaku ryoho. Cancer & chemotherapy,
E H Austin, and
M W Flye
January 2018,
Journal of visualized surgery,
E H Austin, and
M W Flye
February 1985,
Ugeskrift for laeger,
E H Austin, and
M W Flye
May 2013,
Deutsches Arzteblatt international,
E H Austin, and
M W Flye
January 2018,
AACN advanced critical care,
E H Austin, and
M W Flye
January 2005,
Surgery today,
