-transparent.png){kind=logo}
We examined peripheral blood and bronchoalveolar lavage (BAL) fluid lymphocyte subpopulations in 29 asbestos workers, 10 with and 19 without clinical or radiologic evidence of asbestosis. Peripheral blood lymphocyte subpopulations were also measured in 13 control subjects. The mean OKT4:OKT8 (T-helper/inducer:T-suppressor/cytotoxic lymphocyte) ratio in BAL fluid in the 29 asbestos workers was 0.96 (range, not detected to 3.33), significantly less than 1.76 (1.33 to 2.67) in peripheral blood (p less than 0.001). There were no significant differences in OKT4:OKT8 ratios in peripheral blood between the 10 patients with asbestosis, the 19 asbestos workers without asbestosis, and the 13 normal control subjects or in the OKT4:OKT8 ratios in BAL fluid between patients with asbestosis and asbestos workers without asbestosis. In the group as a whole, 83% of those who had suffered more than 5 yr of exposure to asbestos showed OKT4:OKT8 ratios less than 1.2, whereas in those who had suffered fewer than 5 yr of exposure, 80% showed ratios greater than 1.2 (p less than 0.02). No other relationships between OKT4:OKT8 ratios and clinical, radiographic, or physiologic variables were observed.
A R Gellert, and
M G Macey, and
S Uthayakumar, and
A C Newland, and
R M Rudd
March 1994,
Deutsche medizinische Wochenschrift (1946),
A R Gellert, and
M G Macey, and
S Uthayakumar, and
A C Newland, and
R M Rudd
October 2020,
La Medicina del lavoro,
A R Gellert, and
M G Macey, and
S Uthayakumar, and
A C Newland, and
R M Rudd
March 1986,
British journal of industrial medicine,
A R Gellert, and
M G Macey, and
S Uthayakumar, and
A C Newland, and
R M Rudd
December 1991,
Zentralblatt fur Hygiene und Umweltmedizin = International journal of hygiene and environmental medicine,
A R Gellert, and
M G Macey, and
S Uthayakumar, and
A C Newland, and
R M Rudd
October 2011,
Toxicology and industrial health,
A R Gellert, and
M G Macey, and
S Uthayakumar, and
A C Newland, and
R M Rudd
March 1999,
Archivos de bronconeumologia,
A R Gellert, and
M G Macey, and
S Uthayakumar, and
A C Newland, and
R M Rudd
January 1989,
The American review of respiratory disease,
A R Gellert, and
M G Macey, and
S Uthayakumar, and
A C Newland, and
R M Rudd
January 1997,
La Medicina del lavoro,
A R Gellert, and
M G Macey, and
S Uthayakumar, and
A C Newland, and
R M Rudd
January 1986,
Acta cytologica,
A R Gellert, and
M G Macey, and
S Uthayakumar, and
A C Newland, and
R M Rudd
January 1983,
Allergie und Immunologie,
