28 sailors, members of the six crews who took part in long voyages round the world, including the Cape Horn passage, were put by the author under examination. In the group examined there were found following psychopathological disorders: depressive syndromes, asthenic states, neurosis syndromes and perception disturbances and in one case--a psychotic state. The disorders mentioned above were short-lived and did not cause serious disturbances. The etiology of the psychopathological disturbances occurring in the sailors during long voyages is complex and is a resultant of many factors: social isolation, deprivation of needs, change of the way of life, navigational and meteorological conditions and motivational and personality factors.