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A highly sensitive ratiometric fluorescence immunoassay based on bioorthogonal nanozymes. 2024
Xiajian Liu, and
Nianhua Wang, and
Yixuan Hou, and
He Dong, and
Wenhua Liang, and
Xinchun Li, and
Youyong Yuan
School of Biomedical Sciences and Engineering, Guangzhou International Campus, South China University of Technology, Guangzhou, 511442, P. R. China. yuanyy@scut.edu.cn.
We designed a novel ratiometric fluorescence immunoassay based on bioorthogonal nanozymes for carcinoembryonic antigen detection. The analytical performance of our designed immunoassay showed a wide linear range, a low detection limit, good reproducibility, selectivity and stability. Thus, bioorthogonal nanozymes hold great potential applications in clinical diagnoses.
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