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Left ventricular function in 53 patients with secundum atrial septal defect was assessed by computer-assisted analysis of the left ventricular echocardiogram and by cardiac catheterization. The patients were divided into two groups, those younger and those older than 60 years, to investigate the effect of aging on left ventricular function. Cavity size was significantly smaller than normal (p less than 0.01) and septal motion was abnormal in 86%, but values for cardiac index, left ventricular end-diastolic pressure, velocity of circumferential fiber shortening, left ventricular filling rate, and duration of rapid filling were normal in both groups. Regional dynamics assessed in terms of peak rates of systolic thickening and diastolic thinning of the septum and posterior wall were also normal in both groups. We concluded that, although left ventricular minor dimensions are small, and septal motion is reversed in the majority of patients with atrial septal defect, left ventricular function is normal, and it does not appear to deteriorate with increased age, pulmonary hypertension, or the presence of right ventricular failure. The abnormal septal motion appears to be compensated for by enhanced septal and posterior wall percentage thickening.
M G St John Sutton, and
A J Tajik, and
L A Mercier, and
J B Seward, and
E R Giuliani, and
E L Ritman
January 1984,
Kyobu geka. The Japanese journal of thoracic surgery,
M G St John Sutton, and
A J Tajik, and
L A Mercier, and
J B Seward, and
E R Giuliani, and
E L Ritman
October 1980,
[Zasshi] [Journal]. Nihon Kyobu Geka Gakkai,
M G St John Sutton, and
A J Tajik, and
L A Mercier, and
J B Seward, and
E R Giuliani, and
E L Ritman
July 2009,
Circulation journal : official journal of the Japanese Circulation Society,
M G St John Sutton, and
A J Tajik, and
L A Mercier, and
J B Seward, and
E R Giuliani, and
E L Ritman
January 1998,
Gynecologic and obstetric investigation,
M G St John Sutton, and
A J Tajik, and
L A Mercier, and
J B Seward, and
E R Giuliani, and
E L Ritman
September 1982,
Cardiologia (Rome, Italy),
M G St John Sutton, and
A J Tajik, and
L A Mercier, and
J B Seward, and
E R Giuliani, and
E L Ritman
December 1975,
Pediatric research,
M G St John Sutton, and
A J Tajik, and
L A Mercier, and
J B Seward, and
E R Giuliani, and
E L Ritman
September 1967,
British heart journal,
M G St John Sutton, and
A J Tajik, and
L A Mercier, and
J B Seward, and
E R Giuliani, and
E L Ritman
March 2024,
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M G St John Sutton, and
A J Tajik, and
L A Mercier, and
J B Seward, and
E R Giuliani, and
E L Ritman
August 2005,
The American journal of cardiology,
M G St John Sutton, and
A J Tajik, and
L A Mercier, and
J B Seward, and
E R Giuliani, and
E L Ritman
May 1982,
Clinical physics and physiological measurement : an official journal of the Hospital Physicists' Association, Deutsche Gesellschaft fur Medizinische Physik and the European Federation of Organisations for Medical Physics,
