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A killed E. coli 0111:K58 vaccine was administered by the oral route to 16 children ranging from 3 months to 7 years of age. The antibody response was measured at different times after the vaccination through the titration of agglutinating antibodies in serum and in fecal extracts, and the detection of specific IgA immunoglobulins in the intestinal content. All vaccines developed antibody response detectable both inserum and in fecal samples. Coproantibodies tended to appear earlier and to attain higher titers than circulating antibodies; they were all least in part IgA immunoglobulins, since the content of specific IgA in the fecal extracts was proportional to the agglutinating titer.
C Iannuzzi, and
S Barbaro, and
I Viano, and
M Zucca, and
M G Marazzi, and
D Fonzo, and
A Campelli, and
M Lenti Bologna, and
F Dianzani
January 1967,
Acta microbiologica Academiae Scientiarum Hungaricae,
C Iannuzzi, and
S Barbaro, and
I Viano, and
M Zucca, and
M G Marazzi, and
D Fonzo, and
A Campelli, and
M Lenti Bologna, and
F Dianzani
April 1987,
East African medical journal,
C Iannuzzi, and
S Barbaro, and
I Viano, and
M Zucca, and
M G Marazzi, and
D Fonzo, and
A Campelli, and
M Lenti Bologna, and
F Dianzani
January 1975,
Archives roumaines de pathologie experimentales et de microbiologie,
C Iannuzzi, and
S Barbaro, and
I Viano, and
M Zucca, and
M G Marazzi, and
D Fonzo, and
A Campelli, and
M Lenti Bologna, and
F Dianzani
May 1975,
Minerva pediatrica,
C Iannuzzi, and
S Barbaro, and
I Viano, and
M Zucca, and
M G Marazzi, and
D Fonzo, and
A Campelli, and
M Lenti Bologna, and
F Dianzani
May 1968,
Zhurnal mikrobiologii, epidemiologii i immunobiologii,
C Iannuzzi, and
S Barbaro, and
I Viano, and
M Zucca, and
M G Marazzi, and
D Fonzo, and
A Campelli, and
M Lenti Bologna, and
F Dianzani
January 1985,
Acta virologica,
C Iannuzzi, and
S Barbaro, and
I Viano, and
M Zucca, and
M G Marazzi, and
D Fonzo, and
A Campelli, and
M Lenti Bologna, and
F Dianzani
June 1988,
Vaccine,
C Iannuzzi, and
S Barbaro, and
I Viano, and
M Zucca, and
M G Marazzi, and
D Fonzo, and
A Campelli, and
M Lenti Bologna, and
F Dianzani
June 1980,
Archives of disease in childhood,
C Iannuzzi, and
S Barbaro, and
I Viano, and
M Zucca, and
M G Marazzi, and
D Fonzo, and
A Campelli, and
M Lenti Bologna, and
F Dianzani
April 2002,
Infection and immunity,
C Iannuzzi, and
S Barbaro, and
I Viano, and
M Zucca, and
M G Marazzi, and
D Fonzo, and
A Campelli, and
M Lenti Bologna, and
F Dianzani
January 1967,
Acta microbiologica Academiae Scientiarum Hungaricae,
