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Serial Bronchoalveolar Lavage Fluid Aspergillus Galactomannan and Treatment Response in Invasive Pulmonary Aspergillosis. 2024

Daniel Z P Friedman, and Elitza S Theel, and Randall C Walker, and Holenarasipur R Vikram, and Raymund R Razonable, and Paschalis Vergidis
Section of Infectious Disease, Department of Medicine, Mayo Clinic, Rochester, Minnesota, USA.

We studied patients diagnosed with aspergillosis based on positive bronchoalveolar lavage (BAL) Aspergillus galactomannan (GM) who had follow-up BAL sampling within 180 days. GM trend and clinical outcome were concordant in only 60% (30/50). While useful for the initial diagnosis, BAL GM trending does not always correlate with treatment response.

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