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Salvage Therapy Including Foscarnet and Ibalizumab for Multidrug-Resistant Human Immunodeficiency Virus Type 2 Infection. 2024
Antoine Bachelard, and
Quentin Le Hingrat, and
Valentine-Marie Ferré, and
Minh Lê, and
Gilles Peytavin, and
Florence Damond, and
Charlotte Charpentier, and
Guillemette Fremont Goudot, and
Jeanne Goupil de Bouille, and
Sylvie Lariven, and
Pierre Delobel, and
Yazdan Yazdanpanah, and
Diane Descamps, and
Sophie Matheron, and
Jade Ghosn, and
Assistance Publique-Hôpitaux de Paris.Nord, Service des Maladies Infectieuses et Tropicales, Hôpitaux Universitaires Paris Nord Val de Seine, site Bichat-Claude Bernard, Paris, France.
We evaluated Ibalizumab (IBA)-containing standardized optimized salvage regimen (with or without a 4-week foscarnet induction) in individuals harboring multidrug-resistant human immunodeficiency virus type 2 (HIV-2). Nine were included; 2 achieved virological suppression after foscarnet induction with a sustained suppression at Week 24 after IBA initiation, and an additional individual at Week 24 after Ibalizumab initiation.
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