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Mianserin--a new tetracyclic antidepressant. 1979

M Fink

UI MeSH Term Description Entries
D008803 Mianserin A tetracyclic compound with antidepressant effects. It may cause drowsiness and hematological problems. Its mechanism of therapeutic action is not well understood, although it apparently blocks alpha-adrenergic, histamine H1, and some types of serotonin receptors. Lerivon,Mianserin Hydrochloride,Mianserin Monohydrochloride,Org GB 94,Tolvon,Hydrochloride, Mianserin,Monohydrochloride, Mianserin
D002986 Clinical Trials as Topic Works about pre-planned studies of the safety, efficacy, or optimum dosage schedule (if appropriate) of one or more diagnostic, therapeutic, or prophylactic drugs, devices, or techniques selected according to predetermined criteria of eligibility and observed for predefined evidence of favorable and unfavorable effects. This concept includes clinical trials conducted both in the U.S. and in other countries. Clinical Trial as Topic
D003863 Depression Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders. Depressive Symptoms,Emotional Depression,Depression, Emotional,Depressive Symptom,Symptom, Depressive
D003984 Dibenzazepines Compounds with two BENZENE rings fused to AZEPINES.
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man

Related Publications

M Fink
Clinical experience with Org GB94 (mianserin hydrochloride), a new tetracyclic antidepressant.
January 1978, Folia psychiatrica et neurologica japonica,
M Fink
Efficacy and side effects of mianserin, a tetracyclic antidepressant.
April 1983, Postgraduate medical journal,
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Inhibition of cardiac hERG potassium channels by tetracyclic antidepressant mianserin.
July 2008, Naunyn-Schmiedeberg's archives of pharmacology,
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Interaction between the tetracyclic antidepressant mianserin HCl and opioid receptors.
December 1998, European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology,
M Fink
[Report on a preliminary open clinical study of mianserin (GB 94), a tetracyclic antidepressant].
December 1973, Arzneimittel-Forschung,
M Fink
[Tricyclic antidepressant, tetracyclic antidepressant].
August 2001, Nihon rinsho. Japanese journal of clinical medicine,
M Fink
PET evaluation of a tetracyclic, atypical antidepressant, [N-methyl-11C]mianserin, in the living porcine brain.
April 2002, Nuclear medicine and biology,
M Fink
Reversal of morphine-induced suppression of active avoidance behaviour by the tetracyclic antidepressant mianserin [proceedings].
March 1977, British journal of pharmacology,
M Fink
Antitumor activity of mianserin (a tetracyclic antidepressant) primarily driven by the inhibition of SLC1A5-mediated glutamine transport.
October 2022, Investigational new drugs,
M Fink
Electrophysiological studies on the effects of mianserin, a tetracyclic antidepressant agent, on isolated guinea-pig papillary muscle.
September 1988, European journal of pharmacology,
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