-transparent.png){kind=logo}
Intravenous bolus injection of an 80- to 120-mg/m2 dose of cisplatin followed by "rescue" with sodium thiosulfate (STS) was tried in the treatment of 7 patients with advanced tumor. STS was given continuously i.v. six hours after cisplatin injection, combined with methylprednisolone and metoclopramide as antiemetics. Four patients were evaluable, consisting of one CR, one PR and two NC. Severe nausea and emesis occurred in two patients and irreversible renal dysfunction occurred in one. The clinical use of the STS rescue regimen was discussed in conjunction with our basic investigation of "STS-rescue" in an animal model.
Related Publications
K Lee, and
T Kubota, and
F Yoshimine, and
M Sawamura, and
K Tsuchimoto, and
H Toyoda, and
T Miyagawa, and
E Kobayashi, and
K Kadowaki, and
E Kawamura
February 1985,
Journal of clinical oncology : official journal of the American Society of Clinical Oncology,
K Lee, and
T Kubota, and
F Yoshimine, and
M Sawamura, and
K Tsuchimoto, and
H Toyoda, and
T Miyagawa, and
E Kobayashi, and
K Kadowaki, and
E Kawamura
June 1985,
Nihon Hinyokika Gakkai zasshi. The japanese journal of urology,
K Lee, and
T Kubota, and
F Yoshimine, and
M Sawamura, and
K Tsuchimoto, and
H Toyoda, and
T Miyagawa, and
E Kobayashi, and
K Kadowaki, and
E Kawamura
January 1990,
Critical reviews in oncology/hematology,
K Lee, and
T Kubota, and
F Yoshimine, and
M Sawamura, and
K Tsuchimoto, and
H Toyoda, and
T Miyagawa, and
E Kobayashi, and
K Kadowaki, and
E Kawamura
October 1986,
American journal of clinical oncology,
K Lee, and
T Kubota, and
F Yoshimine, and
M Sawamura, and
K Tsuchimoto, and
H Toyoda, and
T Miyagawa, and
E Kobayashi, and
K Kadowaki, and
E Kawamura
January 1991,
Journal of cancer research and clinical oncology,
K Lee, and
T Kubota, and
F Yoshimine, and
M Sawamura, and
K Tsuchimoto, and
H Toyoda, and
T Miyagawa, and
E Kobayashi, and
K Kadowaki, and
E Kawamura
November 1984,
Cancer treatment reports,
K Lee, and
T Kubota, and
F Yoshimine, and
M Sawamura, and
K Tsuchimoto, and
H Toyoda, and
T Miyagawa, and
E Kobayashi, and
K Kadowaki, and
E Kawamura
December 1982,
Annals of internal medicine,
K Lee, and
T Kubota, and
F Yoshimine, and
M Sawamura, and
K Tsuchimoto, and
H Toyoda, and
T Miyagawa, and
E Kobayashi, and
K Kadowaki, and
E Kawamura
January 1988,
Acta oncologica (Stockholm, Sweden),
K Lee, and
T Kubota, and
F Yoshimine, and
M Sawamura, and
K Tsuchimoto, and
H Toyoda, and
T Miyagawa, and
E Kobayashi, and
K Kadowaki, and
E Kawamura
September 1985,
European journal of cancer & clinical oncology,
K Lee, and
T Kubota, and
F Yoshimine, and
M Sawamura, and
K Tsuchimoto, and
H Toyoda, and
T Miyagawa, and
E Kobayashi, and
K Kadowaki, and
E Kawamura
November 1991,
Gynecologic oncology,
