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The morphology of the glands in 9 male rats was studied after 3 months of streptozotocin-induced diabetes mellitus and compared with that of 9 control rats and 6 streptozotocin-treated, non-diabetic rats which served as controls for any effect of streptozotocin not due to diabetes mellitus. In the diabetic group, mean salivary-gland weight and volume was reduced. There was an increase in the ratio of mean volume to total gland volume for seromucous acini (p less than 0.01), intra-lobular striated ducts (p less than 0.001), fat (p less than 0.001) and blood vessels (p less than 0.01), and a decrease in both granular duct (p less than 0.001) and intercalated duct (p less than 0.01) volume ratios. There was a marked reduction in the total length of granular ducts (p less than 0.001) and an increase in the length of striated ducts (p less than 0.001). Measurements from the streptozotocin-treated, non-diabetic group did not differ significantly from those of controls. These effects may be attributable to failure of growth and chronic sodium depletion.
A S High, and
J Sutton, and
A H Hopper
March 1998,
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme,
A S High, and
J Sutton, and
A H Hopper
December 2022,
Drug delivery,
A S High, and
J Sutton, and
A H Hopper
June 2009,
Cell biochemistry and function,
A S High, and
J Sutton, and
A H Hopper
January 1987,
Arquivos do Centro de Estudos do curso de odontologia,
A S High, and
J Sutton, and
A H Hopper
January 1989,
Revista da Faculdade de Odontologia de Lins,
A S High, and
J Sutton, and
A H Hopper
April 2015,
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology,
A S High, and
J Sutton, and
A H Hopper
May 2021,
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie,
A S High, and
J Sutton, and
A H Hopper
December 2023,
Journal of experimental zoology. Part A, Ecological and integrative physiology,
A S High, and
J Sutton, and
A H Hopper
September 2017,
Biochemical and biophysical research communications,
A S High, and
J Sutton, and
A H Hopper
August 2010,
Cell biochemistry and function,
