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One hundred midtrimester pregnancy terminations were successfully induced with continuous extraovular infusion of prostaglandin F2 alpha (PGF2 alpha). The solution was infused into the extraovular space with a newly developed double-balloon catheter. The mean instillation abortion time was 12.9 h. Abortion was completed in 48% of the patients within 12 h, in 80% within 18 h, and in 96% within 24 h. The mean total dose of PGF2 alpha instilled was 12.4 mg/patient. Only four patients aborted after 24 h from the insertion of the catheter and instillation of the PGF2 alpha. Side effects were few. Thirteen patients (13%) had nausea and vomiting, and 14 (14%) had transient pyrexia (above 38 C). No major complications occurred. It appears that this method has a high success rate, good patient tolerance, and an acceptable safety factor with few minor side effects.
J Atad, and
A Lissak, and
Y Sorokin, and
J Bornstein, and
R Auslender, and
A Rofe, and
H Abramovici
April 1979,
Journal of obstetrics and gynaecology of India,
J Atad, and
A Lissak, and
Y Sorokin, and
J Bornstein, and
R Auslender, and
A Rofe, and
H Abramovici
June 1974,
The New Zealand medical journal,
J Atad, and
A Lissak, and
Y Sorokin, and
J Bornstein, and
R Auslender, and
A Rofe, and
H Abramovici
May 1974,
Prostaglandins,
J Atad, and
A Lissak, and
Y Sorokin, and
J Bornstein, and
R Auslender, and
A Rofe, and
H Abramovici
May 1981,
The Australian & New Zealand journal of obstetrics & gynaecology,
J Atad, and
A Lissak, and
Y Sorokin, and
J Bornstein, and
R Auslender, and
A Rofe, and
H Abramovici
September 1998,
Journal of maternal-fetal investigation : the official journal of French Society of Ultrasound in Medicine and Biology ... [et al.],
J Atad, and
A Lissak, and
Y Sorokin, and
J Bornstein, and
R Auslender, and
A Rofe, and
H Abramovici
January 1980,
International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics,
J Atad, and
A Lissak, and
Y Sorokin, and
J Bornstein, and
R Auslender, and
A Rofe, and
H Abramovici
August 1974,
Ceskoslovenska gynekologie,
J Atad, and
A Lissak, and
Y Sorokin, and
J Bornstein, and
R Auslender, and
A Rofe, and
H Abramovici
January 1975,
Advances in planned parenthood,
J Atad, and
A Lissak, and
Y Sorokin, and
J Bornstein, and
R Auslender, and
A Rofe, and
H Abramovici
April 1975,
Journal of obstetrics and gynaecology of India,
J Atad, and
A Lissak, and
Y Sorokin, and
J Bornstein, and
R Auslender, and
A Rofe, and
H Abramovici
May 1982,
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde,
