-transparent.png){kind=logo}
Nickel-Catalyzed Enantioselective Reductive Arylation of Common Ketones. 2024
State Key Laboratory of Chemical Oncogenomics, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, 2199 Lishui Road, Nanshan District, Shenzhen 518055, China.
A nickel complex of chiral bisoxazolines catalyzed the stereoselective reductive arylation of ketones in high enantioselectivity. A range of common acyclic and cyclic ketones reacted without the aid of directing groups. Mechanistic studies using isolated complex of a chiral bis(oxazoline) (L)Ni(Ar)Br revealed that Mn reduction was not needed, while Lewis acidic titanium alkoxides were critical to ketone insertion.
| UI | MeSH Term | Description | Entries |
|---|
Related Publications
Shuai Huang, and
Jianrong Steve Zhou
September 2016,
Angewandte Chemie (International ed. in English),
Shuai Huang, and
Jianrong Steve Zhou
January 2016,
Beilstein journal of organic chemistry,
Shuai Huang, and
Jianrong Steve Zhou
July 2016,
Chemical science,
Shuai Huang, and
Jianrong Steve Zhou
April 2023,
Journal of the American Chemical Society,
Shuai Huang, and
Jianrong Steve Zhou
December 2023,
Organic letters,
Shuai Huang, and
Jianrong Steve Zhou
November 2022,
Journal of the American Chemical Society,
Shuai Huang, and
Jianrong Steve Zhou
August 2020,
ACS catalysis,
Shuai Huang, and
Jianrong Steve Zhou
August 2016,
Organic & biomolecular chemistry,
Shuai Huang, and
Jianrong Steve Zhou
June 2014,
Angewandte Chemie (International ed. in English),
Shuai Huang, and
Jianrong Steve Zhou
January 2008,
Journal of the American Chemical Society,
