Biomaterial Database

Hormonal and type-dependent adhesion of group B streptococci to human vaginal cells. 1979

G A Botta

Adhesion of group B streptococci to epithelial cells of the human vagina proved to be type dependent and to fluctuate during the menstrual cycle with a maximum near the time of ovulation. Oral contraception completely abolished the observed cyclic changes. Reduced serum levels of luteinizing hormones (less than 5 mIU/ml) and of follicle-stimulating hormone (less than 10 mIU/ml) were associated with a 10-fold reduction in adhesion of B streptococci to vaginal cells.

UI	MeSH Term	Description	Entries
D007986	Luteinizing Hormone	A major gonadotropin secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). Luteinizing hormone regulates steroid production by the interstitial cells of the TESTIS and the OVARY. The preovulatory LUTEINIZING HORMONE surge in females induces OVULATION, and subsequent LUTEINIZATION of the follicle. LUTEINIZING HORMONE consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is common in the three pituitary glycoprotein hormones (TSH, LH and FSH), but the beta subunit is unique and confers its biological specificity.	ICSH (Interstitial Cell Stimulating Hormone),Interstitial Cell-Stimulating Hormone,LH (Luteinizing Hormone),Lutropin,Luteoziman,Luteozyman,Hormone, Interstitial Cell-Stimulating,Hormone, Luteinizing,Interstitial Cell Stimulating Hormone
D008598	Menstruation	The periodic shedding of the ENDOMETRIUM and associated menstrual bleeding in the MENSTRUAL CYCLE of humans and primates. Menstruation is due to the decline in circulating PROGESTERONE, and occurs at the late LUTEAL PHASE when LUTEOLYSIS of the CORPUS LUTEUM takes place.
D003276	Contraceptives, Oral	Compounds, usually hormonal, taken orally in order to block ovulation and prevent the occurrence of pregnancy. The hormones are generally estrogen or progesterone or both.	Low-Dose Oral Contraceptive,Oral Contraceptive,Oral Contraceptives,Oral Contraceptives, Low-Dose,Oral Contraceptives, Phasic,Contraceptive, Low-Dose Oral,Contraceptive, Oral,Contraceptives, Low-Dose Oral,Contraceptives, Phasic Oral,Low Dose Oral Contraceptive,Low-Dose Oral Contraceptives,Oral Contraceptive, Low-Dose,Oral Contraceptives, Low Dose,Phasic Oral Contraceptives
D005260	Female		Females
D005640	Follicle Stimulating Hormone	A major gonadotropin secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). Follicle-stimulating hormone stimulates GAMETOGENESIS and the supporting cells such as the ovarian GRANULOSA CELLS, the testicular SERTOLI CELLS, and LEYDIG CELLS. FSH consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is common in the three pituitary glycoprotein hormones (TSH, LH, and FSH), but the beta subunit is unique and confers its biological specificity.	FSH (Follicle Stimulating Hormone),Follicle-Stimulating Hormone,Follitropin
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D012703	Serotyping	Process of determining and distinguishing species of bacteria or viruses based on antigens they share.	Serotypings
D013292	Streptococcus agalactiae	A bacterium which causes mastitis in cattle and occasionally in man.	Streptococcus Group B
D014621	Vagina	The genital canal in the female, extending from the UTERUS to the VULVA. (Stedman, 25th ed)	Vaginas

Related Publications

G A Botta

[Adhesion of group B streptococci to vaginal epithelial cells].

December 1984, Zhurnal mikrobiologii, epidemiologii i immunobiologii,

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Factors influencing adherence of group B streptococci to human vaginal epithelial cells.

November 1979, Infection and immunity,

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Adherence of vaginal and pharyngeal strains of group B streptococci to human vaginal and pharyngeal epithelial cells.

November 1986, Zentralblatt fur Bakteriologie, Mikrobiologie, und Hygiene. Series A, Medical microbiology, infectious diseases, virology, parasitology,

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Cyclic variation in the adherence of group B streptococci to human vaginal epithelial cells.

June 1981, American journal of obstetrics and gynecology,

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Group B streptococci and vaginal discharge.

April 1987, Genitourinary medicine,

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Type-specific antibodies against group B streptococci in human serum, saliva and vaginal secretions.

January 1987, Advances in experimental medicine and biology,

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The adhesin structures involved in the adherence of group B streptococci to human vaginal cells.

January 1986, Folia microbiologica,